Review paper (Pregledni rad)
Marijana Hrga1, Tatjana Matijaš1
1 University of Split, University Department of Health Studies, Split, Croatia
Corresponding author: Tatjana Matijaš, University of Split, University Department of Health Studies, Split, Croatia, email:
DOI: https://doi.org/10.55378/rv.48.2.4
Summary
Cervical cancer is one of the most common malignant tumours in women. The treatment of early and locally advanced stages of this cancer typically involves surgery, chemotherapy, and radiotherapy. However, there is no standardised therapy for metastatic cervical cancer due to the diverse manifestations of the disease. Therefore, timely diagnosis and staging of the carcinoma are crucial for maintaining the quality of life of patients. Imaging during the initial diagnostic evaluation is essential for accurately assessing the extent of the tumour and metastases, and for selecting the optimal therapy, with the FIGO system further emphasising this role. Compared to other imaging techniques, MRI provides detailed information on the location and size of the tumour, invasion into surrounding tissues, and the presence of distant metastases. This allows MRI to facilitate a tailored approach in therapy selection, taking into account the specific characteristics of the tumour. The integration of MRI into the diagnostic and therapeutic process improves clinical outcomes for patients with cervical cancer, enabling effective care. MRI is used alongside other imaging modalities in the diagnosis and treatment planning, and without it, precise staging of the disease and establishing a final diagnosis would not be possible.
Keywords: FIGO staging, cervical cancer, magnetic resonance, PET/CT, US
Važnost MR-a u određivanju stadija raka vrata maternice
Sažetak
Rak vrata maternice jedan je od najčešćih malignih tumora koji pogađa žene. Kod bolesnica s ranim stadijem raka vrata maternice i lokalno uznapredovalim rakom vrata maternice princip liječenja je konvencionalan uključujući operaciju, kemoterapiju i radioterapiju, dok kod bolesnica s metastatskim rakom vrata maternice, ne postoji standardno liječenje zbog njegovih heterogenih manifestacija. Zbog svega toga ključno je na vrijeme dijagnosticirati i odrediti stadij karcinoma u svrhu kvalitete života. Snimanje tijekom primarne dijagnostičke obrade ključno je za točnu procjenu proširenosti tumora i metastatske bolesti kao i za odabir najbolje terapijske opcije, a pomoću FIGO sustava njegova je uloga dodatno naglašena. U odnosu na druge tehnike snimanja, MR nam pruža detaljne informacije o lokalizaciji i veličini tumora, invaziji u okolna tkiva, te prisutnost udaljenih metastaza. MR doprinosi individualiziranom pristupu u odabiru terapije, uzimajući u obzir specifične karakteristike tumora. Integracija MR-a u dijagnostički i terapijski proces poboljšava kliničke ishode pacijenata s karcinomom vrata maternice, omogućujući učinkovitu skrb. MR se nadopunjuje sa ostalim modalitetima snimanja kod dijagnostike i planiranja liječenja, te bez MR-a nije moguće utvrditi stadij bolesti i postaviti konačnu dijagnozu.
Ključne riječi: FIGO stadij, karcinom vrata maternice, magnetska rezonancija, PET/CT, UZV